Generator Rex - Characters & Cast

Initially, Rex is motivated by a desire for personal freedom and the truth about his forgotten past. As the series progresses, his motivation shifts. He develops a deep-seated need to protect his found family (Six, Holiday, Bobo, and Noah) and a genuine, empathetic drive to cure every E.V.O. he can, seeing them not as monsters but as victims like himself. His ultimate motivation becomes creating a world where no one has to suffer from the nanite infection.

Rex begins the series as a cocky, impulsive teenager who, despite his immense power, feels like a prisoner of Providence. His primary goal is to uncover his past and achieve a semblance of a normal life. Across the series, he matures significantly. He learns the truth about his involvement in the Nanite Event, not as a villain, but as a tragic victim and key component. This knowledge forces him to accept responsibility on a global scale. He transitions from a reluctant weapon into a true leader, culminating in him gaining full control over all nanites on Earth to perform a worldwide cure, a decision that shows his growth from a self-interested teen to a selfless savior.

Six's primary motivation is his unwavering loyalty and a deeply ingrained sense of duty. Initially, this duty is to Providence. Over time, his loyalty transfers directly to Rex and Dr. Holiday. He is driven by a past failure (revealed in the episode "Promises, Promises") to protect those he cares about, making his mission to keep Rex safe intensely personal.

Six starts as Rex's handler, a mysterious and seemingly emotionless agent defined by his lethal efficiency and adherence to Providence protocol. His relationship with Rex is purely professional. However, as the series unfolds, he thaws considerably, revealing a deeply protective and caring nature. He becomes a father figure to Rex, often defying his superiors, like White Knight, to protect him. His arc is about rediscovering his own humanity through his bond with Rex, moving from a simple agent to a core member of Rex's family.

Holiday is driven by a dual motivation: a scientific imperative to solve the nanite problem and a deeply personal need to cure her sister. This combination makes her both a compassionate caregiver and a relentless researcher. Her primary focus is always on the ethical treatment of E.V.O.s and ensuring that Rex is treated as a person, not just a weapon.

Dr. Holiday is introduced as the lead scientist studying Rex and the nanite phenomenon. She is professional, brilliant, and serves as Rex's primary medical overseer. Her arc is one of balancing scientific objectivity with growing emotional attachment. She becomes a maternal figure for Rex, fiercely advocating for his well-being against the more ruthless elements of Providence. Her personal stake in finding a cure is revealed through her incurable E.V.O. sister, giving her a powerful and emotional backstory that drives her scientific pursuits. She evolves from a doctor treating a patient to a mother protecting her son.

Van Kleiss is motivated by a lust for absolute power and a god complex. He was one of the original scientists on the Nanite Project and feels he is the rightful master of their power. He needs to periodically absorb nanites from the ground of Abysus or from other E.V.O.s to survive, creating a constant, parasitic hunger that drives his actions. His ultimate goal is to unlock the secrets of the Meta-Nanites and reshape the world in his own image.

Van Kleiss is the primary antagonist for much of the series. He is intrinsically linked to Rex's past and the Nanite Event. His arc is a descent into obsession. Initially, he presents himself as a revolutionary leader, creating a supposed utopia for E.V.O.s in Abysus. He believes E.V.O.s are the future. However, his true goal is revealed to be achieving godhood by controlling the nanites. He constantly tries to manipulate Rex, believing him to be the key. His arc is not one of change, but of escalating ambition, becoming more monstrous and desperate as his plans are repeatedly foiled, cementing him as a tragic figure who squandered his genius for power.