The entire premise of "Maid Sama!" rests on the secret of Misaki's part-time job as a maid, a secret she keeps out of fear that it will undermine her authority as the formidable Student Council President. The anime's main arc is driven by Takumi Usui's discovery of this secret and his subsequent relationship with Misaki. The anime concludes with Misaki finally confessing her feelings to Usui during the school festival, and they officially become a couple.
However, the anime only covers a fraction of the manga's story. The manga delves deep into Usui's hidden past, which is a major plotline left unresolved in the anime. It is revealed that Usui is the illegitimate son of a wealthy and noble British family, the Walkers. He lives in Japan to have a normal life away from the family's influence, and his family's existence creates significant obstacles for his relationship with Misaki, who is not of the same social standing. This revelation re-contextualizes Usui's character from a mysterious high-school prodigy to a young man escaping a complicated and restrictive heritage.
The manga follows their long-distance relationship after Usui is forced to transfer to Miyabigaoka High and later move to England to be with his family. Misaki, in turn, works incredibly hard to become a successful diplomat. The ultimate finale of the story, as told in the manga, takes place ten years after high school. Misaki has achieved her dream of becoming a diplomat, and Usui has become a renowned doctor for the Walker family. The series concludes with their wedding, surrounded by their friends and family from Seika High, providing a definitive and happy ending to their long and complicated journey.