The central twist of "Me Before You" is the revelation that Will Traynor is resolute in his decision to die by assisted suicide at Dignitas in Switzerland, and that Lou's six-month contract was a final attempt by his parents to change his mind. Despite falling deeply in love with Lou and finding moments of genuine happiness, Will's core belief that his life as a quadriplegic is an unacceptable, diminished existence does not waver. During a trip to Mauritius, a romantic high point for the couple, he confesses that his plan is unchanged. He argues that he cannot be the man she deserves and doesn't want her to lead a 'half-life' tied to his limitations.
Heartbroken, Lou initially leaves, feeling that her love has failed. However, she ultimately chooses to respect his autonomy and travels to Switzerland to be with him in his final moments, a testament to the depth of her love. The film concludes with Lou in Paris, reading a letter from Will. He has left her a substantial inheritance, not as a payment, but as a key to unlock the future he urged her to build. He encourages her to 'live boldly' and 'just live.' This ending solidifies the film's bittersweet theme: their love was real and transformative, but it couldn't change his fundamental decision. His final act is not one of despair alone, but a final act of love—pushing her towards a full life that he felt he could no longer have himself.