As the story progresses, Sue refuses to return to her dormant state after her seven-day period ends. She is selected to host the prestigious televised New Year's Eve Special and needs time to rehearse. Sue overstays her term by several days, extracting stabilizing fluid directly from Elisabeth's unconscious body. When Elisabeth wakes up, she discovers that Sue's rule-breaking has caused Elisabeth’s finger to rapidly age and turn into a rotting, brown, calcified claw.
Despite warnings from the Substance supplier that violating the balance causes permanent, irreversible decay, Sue continues to steal days. Elisabeth’s body deteriorates exponentially; she grows a severe hunchback, loses her hair, and transforms into a grotesque, hag-like figure. Horrified, Elisabeth orders the termination syringe to kill Sue permanently. However, just as she injects half the solution into the dormant Sue, Elisabeth stops, unable to kill the only version of herself that society values.
Sue wakes up partially revived, realizes Elisabeth attempted to terminate her, and flies into a rage. Sue brutally beats Elisabeth to death. Sue then prepares for the live broadcast. However, without Elisabeth alive to produce stabilizer fluid, Sue’s own body begins to disintegrate—her teeth and nails fall out, and her ear detaches.
In panic, Sue runs back to her apartment, collects remaining Substance fluids, and injects them all at once. Instead of creating a new copy, the volatile cocktail causes a chaotic mutation. Sue and Elisabeth’s dead tissue fuse together into a deformed, multi-limbed monstrosity featuring Elisabeth's face protruding from the back of a misshapen body—a creature credited as Monstro Elisasue.
Desperate to be loved, Monstro Elisasue puts on a sparkling gown, cuts out a photo of Elisabeth’s face to wear as a mask, and steps onto the live New Year’s Eve stage. When the mask falls off, the studio audience reacts in terror. A crew member decapitates the monster, but a new head erupts, and Monstro Elisasue's body violently explodes like a pressurized volcano, drenching the entire studio, executives, and audience in massive streams of blood.
The dying head of Monstro Elisasue crawls out of the television center onto the street, dragging itself to Elisabeth’s cracked Walk of Fame star. Looking up at the night sky, Elisabeth’s face smiles peacefully as she melts into a puddle of red goo. The following morning, a street-sweeping vehicle vacuums up the remaining sludge, leaving the worn star clean on the sidewalk.