The entire narrative of "Casino" is a chronicle of an inevitable collapse, a fact established in the opening scene where Ace Rothstein's car explodes. The film then functions as an extended flashback explaining how this point was reached. The downfall of the entire operation hinges on a combination of factors. The mob bosses' greed leads them to appoint an incompetent underling, Artie Piscano, to oversee the skim in Kansas City. Piscano's meticulous but incriminating record-keeping, combined with his mother's loud complaints about his work, leads to an FBI wiretap that exposes the entire conspiracy.
Internally, the empire rots from within. Ace's obsession with control and his tumultuous marriage to Ginger create constant chaos. Ginger's affair with Nicky is the ultimate betrayal that severs the bond between the two friends. Nicky's escalating violence and recklessness, including the unauthorized attempted murder of Ace via a car bomb, force the bosses to act. In the end, the mob cleans house in a bloody montage of assassinations to prevent anyone from testifying. Ginger dies of a "hot dose" (a deliberate drug overdose) in a motel. Nicky and his brother Dominick are lured to a cornfield where they are brutally beaten with baseball bats and buried alive by their own crew. Ace survives the car bomb due to a manufacturing plate under the driver's seat and returns to his life as a sports handicapper, watching as the old Vegas is demolished and replaced by corporate theme parks. The ending signifies that the era of individual power and mob control is over, replaced by impersonal, corporate capitalism.