The film's turning point reveals that John is not just a revolutionary but a man running from the guilt of killing his best friend, Nolan, in Ireland. Nolan had informed on John under torture, and John executed him in retaliation. In Mexico, John encounters Dr. Villega, who similarly betrays the revolution under torture. Instead of killing Villega, John sees Nolan in him and offers him a chance to redeem himself by dying with dignity in a suicide attack on the Colonel's train.
The ending sees the complete destruction of Juan's world: his sons are massacred by the army, and his 'friendship' with John ends when John, mortally wounded, detonates himself to destroy the final obstacle. Juan is left alive, a 'hero' of a revolution he hates, completely alone, asking the universe 'What about me?'—a powerful indictment of the personal cost of political upheaval.