The central mystery of "The Third Man" revolves around the death of Harry Lime. The initial plot twist reveals that Harry is not dead at all; he faked his own funeral to escape the authorities. The "third man" who witnesses insisted was at the accident scene was, in fact, Harry himself, helping his accomplices carry away the body of another man who was buried in his place. Holly Martins discovers this in a stunning reveal when a cat plays by the feet of a figure in a dark doorway, who then steps into the light, revealing the smiling face of Harry Lime.
The second major revelation is the nature of Harry's crimes. Major Calloway eventually convinces Holly of the truth by showing him a children's hospital ward filled with victims of meningitis who were treated with penicillin stolen by Harry's racket and dangerously diluted with water. This horrific truth is what finally shatters Holly's loyalty and turns him against his friend.
The film's climax takes place in Vienna's labyrinthine sewer system, where Holly has agreed to act as bait to lure Harry out for the police. When the trap goes wrong, a chase ensues. Harry shoots and kills Sergeant Paine, and is then wounded by Major Calloway. Trapped and dying, Harry drags himself to a sewer grating but cannot escape. In the final confrontation, a cornered Harry gives Holly a slight nod, and Holly, now holding Sergeant Paine's gun, shoots and kills his former friend. The final scene shows Holly attending Harry's second, real funeral. He waits for Anna afterwards, but in a famously long and silent take, she walks the entire length of the cemetery road and passes him without a single glance, leaving him completely alone.