The drama subverts conventional workplace tropes through significant narrative twists and revelations:
- Kim Seo-wan's Death (Episodes 6–7): Long-term patient Kim Seo-wan, who views Da-eun as his "mediator," is discharged after showing improvement. However, returning to the crushing isolation of exam preparation triggers a fatal relapse, leading him to commit suicide by jumping from a building.
- Da-eun's Dissociation and Involuntary Hospitalization (Episodes 8–10): Da-eun develops severe dissociative amnesia and complicated grief, continuing to buy gifts and set dinner plates for Seo-wan. After wandering into traffic in a daze, she is diagnosed with a severe Major Depressive Episode with catatonic features and admitted as an inpatient to Hayan Hospital, reversing her role from nurse to patient.
- Community Stigma and Staff Solidarity (Episodes 11–12): When Da-eun returns to Unit 53, her psychiatric record is leaked, triggering protests from patients' families. Head Nurse Song Hyo-jin and Dr. Im defend her, asserting that recovering from mental illness deepens a nurse's empathy rather than disqualifying her.
- The Finale: Da-eun embraces her history without shame, Min Deul-re leaves to work on a cruise ship, Yu-chan establishes healthy boundaries at a new job, and the entire ward is bathed in morning sunlight as Da-eun reflects that everyone is a border-crosser between day and night.