Set in Paris during the early 1990s, the film follows the activists of ACT UP-Paris as they wage a desperate war against general indifference to the AIDS epidemic. The narrative centers on the group's heated weekly meetings (General Assemblies) where they debate strategies to force government agencies and pharmaceutical companies to release new treatments and prevention measures.
Amidst the shouts and whistles of political action, a tender romance blossoms between Nathan, a newcomer to the group who is HIV-negative, and Sean, a radical and passionate founding member whose health is rapidly deteriorating. The film oscillates between the collective energy of protests—dousing officials in fake blood and invading offices—and the intimate, heartbreaking reality of Sean's declining health, ultimately merging the political fight with the personal tragedy of loss.
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